研究方向：抗虫生物与抗虫基因资源
抑菌生物及其活性物质资源
从事动物、微生物资源及其活性物质资源研究，发现了1类新的昆虫病原线虫（EPNs），包括1个新属，4个新种，其中1个细菌新种；筛选出21个高效昆虫病原线虫/共生菌株系。在线虫和细菌新种鉴定、抑菌生物活性蛋白的分离纯化与基因克隆、miRNA及其互作mRNA的功能鉴定研究方面发表SCI收录论文47篇，一类核心期刊10篇。与中科院广州化学所合作合成鉴定了4-芳基香豆素类化合物的药理活性，发表SCI收录论文3篇，授权发明专利1项。从昆虫病原线虫共生菌等生物中分离纯化出多种活性多肽、蛋白，授权发明专利2项，实质审查中的专利2项。主持完成国家及省部级课题6项，参与6项。获省部级自然科学二等奖1项。
代表论文：
Zhang KY#*, Baiocchi T#, Lu D, Chang D, Dillman AR*. Differentiating Between Scavengers and Entomopathogenic nematodes: Which is Oscheius chongmingensis? Journal of Invertebrate Pathology. 2019, Sep 10: 107245.
Lin J, Xia J, Zhang T, Zhang KY, Yang Q*，Genome-wide profiling of microRNAs reveals novel insights into the interactions between H9N2 avian influenza virus and avian dendritic cells. Oncogenes. 2018, 37(33): 4562-458.
陈建华，孙捷，吕福娇，高国富，赵明文，张克云*. 桑黄发酵液中凝集素SHL24的分离与生物活性研究. 微生物学通报. 2018,(2):420-427.
詹成修; 熊阳杰; 张涛; 张克云*; 崇明拟异小杆线虫daf-16基因的功能鉴定, 昆虫学报, 2018, (08): 932-940
Zhou GX, Yang H, Wang F, Bao HR, Lin J, Yedid G *, Zhang KY *. Oscheius microvilli n. sp ( Nematoda: Rhabditidae): a facultatively pathogenic nematode from Chongming Island, China. Journal of Nematology. 2017, 49 (1) :33-41
Li PP, Dai CS, Bao HR, Chen L, Gao D, Wang GX, Wang J, Wang H, Yedid G, Zhang KY*. A new species of Pristionchus (Rhabditida: Diplogastridae) and its bacterial symbiont from Yixing, China. Journal of Nematology. 2015, 47(3):184–191
Zhang, Keyun*; Ding, Weixian; Sun, Jie; Zhang, Bin; Lu, Fujiao; Lai,Ren; Zou, Yong; Yedid, Gabriel; Antioxidant and antitumor activities of 4-arylcoumarins and 4-aryl-3,4-dihydrocoumarins. , Biochimie, 2014, 107 Pt B:203-210.
Zhang KY*. Symbiotic Specialization, Stability and Pathogenicity Relationships among Rhabditid Entomopathogenic Nematodes Heterorhabditidoides and Their Symbiotic Bacteria. Journal of Nematology. 2014, 46: 259-259
Zhang KY*, Xiu H. Liu, Jin Tan, Ying Wang, Lei Qiao, Gabriel Yedid, Chen S. Dai, Ru L. Qiu, Xiu W. Yan, Hao W. Tan, Zhen Y. Su, Ren Lai, Guo F. Gao. 2012. Heterorhabditidoides rugaoensis n. sp. (Rhabditida: Rhabditidae), a novel highly pathogenic entomopathogenic nematode member of Rhabditidae. Journal of Nematology. 2012, 44(4):356-368.
Zhang C, Yang S,Xu M, Sun J, Liu H, Liu J, Liu H, Kan F, Sun J, Lai R, Zhang K﹡. 2009. A novel species of Serratia, family Enterobacteriaceae: Serratia nematodiphila sp.nov., symbiotically associated with entomopathogenic nematode Heterorhabditidoides chongmingensis (Rhabditida: Rhabditidae). Int J Syst Evol Microbiol. 2009, 59:1603-1608.
Keyun Zhang﹡,Hui Liu, Jie Sun, Jingrui Liu, Kan Fei, Chongxing Zhang, Mingxu Xu, Jing Sun, Ren Lai, Yidong Wu, Maosong Lin. 2008. Molecular Phylogeny of geographical isolates of Bursaphelenchus xylophilus: implications for origin and transmission of this species in China and worldwide. Journal of Nematology 42 (2): 127-1378.
Zhang C, Liu J, Xu M, Sun J, Yang S, An X, Gao G, Lin M, Lai R, He Z, Wu Y*, Zhang K*. 2008.Heterorhabditidoides chongmingensis gen. nov., sp. nov. (Rhabditida: Rhabditidae), a novel member of the entomopathogenic nematodes, Journal of Invertebrate Pathology , 98: 153-168.
Wang X, Song YZ, Li JX, Liu H, Xu XQ, Lai R*, Zhang KY*. A new family of antimicrobial peptides from skin secretions of Rana pleuraden. Peptides. 2007, 28(10): 2069 - 2074.
Li J X, Xu X Q, Xu C H, Zhou W P, Zhang KY, Yu H N, Zhang Y P, Zheng Y T, Rees H H, Lai R, Yang D M, Wu J, 2007. Anti-infection peptidomics of amphibian skin. Molecular & Cellular Proteomics, 2007, 6 (5): 882 - 894
